医学检验科、输血科主任、细胞治疗中心副主任兼任国际部专家、博士、研究员、教授、博士研究生导师、海南省“515人才工程”第二层次人才、海南省高层次人才D类人才、海南省杨焕明院士团队创新中心负责人、海南省肿瘤数字疗法临床试验中心负责人、海南省临床检验诊断学专家、海南省卫健委病原微生物实验室生物安全评审专家、海南省卫健委产前诊断评审专家、中国合格评定国家认可委员会ISO15189医学实验室质量与能力认可技术评审员。
多年来，立足临床检验诊断工作的同时，在鼻咽癌、乳腺癌致病机制、地中海贫血分子诊断和防治领域、干细胞临床转化取得了多项创新研究成果；主持承担多项国家自然科学基金委和海南省科技厅科研项目，以第一作者或通讯作者发表SCI论文24篇，最高影响因子24分，其中多篇文章在Frontiers in Cell and Developmental Biology、Molecular Therapy-Oncolytic 等肿瘤医学国际主流期刊发表。
擅长临床检验诊断学、细胞治疗、临床分子诊断、实验室质量管理、医学遗传学、遗传咨询、法医物证鉴定（亲权鉴定）。
一、肿瘤发病机制及肿瘤靶向药物与早期筛查试剂盒研发
二、肠道微生态与肿瘤关系的机制研究
三、干细胞临床转化应用研究
四、各类病原体早期诊断试剂盒研发
五、产前筛查与产前诊断新技术与试剂盒研究
六、重大遗传病诊断与治疗研究
一、海南省医学会检验医学分会副主任委员
二、海南省抗癌协会肿瘤标志物与分子医学专业委员会主任委员
三、海南省非公医疗检验医学专业委员会主任委员
四、中国非公立医疗机构协会生物样本资源科技分会第一届委员会副会长
五、中国非公立医疗机构协会检验医学分会首席专家兼常委
六、白求恩精神研究会检验医学分会POCT专业委员会副主任委员
七、海南省司法鉴定协会法医物证鉴定专家委员会副主任委员
八、海南省遗传学会常务理事兼秘书长
九、医学参考报检验医学专刊第五届编委会编委
1. Xinping Chen, Weihua Xu, Dafeng Xu, Xianhe Xie, Jia Yao, Shengmiao Fu*. GSTM1 polymorphism and lung cancer risk in the Chinese population: A meta-analysis based on 47 studies. APJCP, 2014,15(18), 7741-7746. (SCI IF:1.5)
2. Chen XP, Xu DF, Xu WH, Yao J, Fu SM*. Glutathione-S-transferases M1/T1 gene polymorphisms and endometriosis: a meta-analysis in Chinese populations. Gynecol Endocrinol, 2015, 31(11): 840–845. (SCI IF:1.33)
3. Hongxia Yao*, Xingping Chen, Lie Lin, Congming Wu, Xiangjun Fu, Hua Wang, Zhiming Yao. The spectrum of α- and β-thalassemia mutations of the Li people in Hainan Province of China. Blood Cells. Molecules and Diseases, 2014, 53, 16-20. （共同第一作者）(SCI IF:2.39)
4. Xinping Chen, Dafeng Xu, Weihua Xu, Zhichao Ma, Jia Yao, Shengmiao Fu*. Association studies of CYP1A1 exon7 polymorphism and -GSTM1 interaction with esophageal cancer risk: a meta-analysis in the Chinese population. Clin. Lab, 2016, 62: 1795-1802. (SCI IF:1.1)
5. Xinping Chen, Weihua Xu, Dafeng Xu, Shengmiao Fu*, Zhichao Ma. G12V KRAs mutations in cervical cancer under virtual microscope of molecular dynamic simulations. European journal of gynaecological oncology. 2016,1:69-74 .(SCI IF:0.9)
6. Xin-Ping Chen, Hai-Feng Wen, Fan Zhang, Wei-Hua Xu, Zhi-Chao Ma, Sheng-Miao Fu*. Assessment of the Link between XRCC1 Arg399Gln Polymorphism and Breast Cancer: a Meta-Analysis in a Single Ethnic Group. Clin. Lab, 2017;63:725-731. (SCI IF:1.1)
7. XinPing Chen, JunJie Hu, Juan Zhu, WeiHua Xu, HongXia Yao, AiZhu Wu, MeiFang Xiao, Zhe Lu, LiYan Yin*, ShengMiao Fu*. Severe Hemolytic Anemia due to combined α thalassemia and de novo Hemoglobin Sabine. Annals of Hematology, 2019, 98(3): 783-785. (SCI IF: 2.85)
8. Xinping Chen, Zhichao Ma, Juan Zhu, Weihua Xu, Junjie Hu, Liyan Yin* and Shengmiao Fu*. Study on the antitumor activity and mechanism of novel targeted nanodrugs based on miRNA in cervical cancer. Materials Express, 2020,10 (8):1218-1223. (SCI IF:1.65)
9. Xinping Chen, Zhangli Lin, Junjie Hu, Shiping Chen, Shu Wen, Aizhu Wu, Hong
Wu, Jiali Huang, Hanqiang Wang, Jun Sun, Zhiyu Peng, Yan Sun* & Shengmiao Fu*. Report of Two Novel Thalassemia Variants, HBB:c.181delG and HBA1: c.121_126delAA GACC, in Chinese Individuals. Hemoglobin, 2021, 45(1):52-55. (SCI IF:0.53)
10. Xinping Chen, Tao Wu, Lingguo Li, Yu Lin, Zhichao Ma, Jinjin Xu, Hui Li, Ruoyan Chen, Kun Sun, Yuxue Luo, Chen Zhang, Fang Chen, Jiao Wang, Tingyu Kuo, Xiaojuan Li, Chunyu Geng, Feng Lin, Chaojie Huang, Junjie Hu, Jianhua Yin, Ming Liu, Ye Tao, Jiye Zhang, Rijing Ou, Huanming Yang, Jian Wang, Xun Xu, Shengmiao Fu*, Hongyan Jiang*, Xin Jin* and Haiqiang Zhang*. TSS Coverage Analysis in Plasma Cell-free DNA Reveals Disease Severity and Tissue Specificity of COVID-19 Patients. Frontiers in Genetics, 2021, 12: 1-11. (SCI IF:4.599)
11. Xinping Chen, HeQiu Ruan, Zhichao Ma, Junjie Hu, Weihua Xu, Liyan Yin, and Shengmiao Fu*. Polymerase Chain Reaction in the Detection of miR-455-5p and Sphingosine-1 Phosphate. Journal of Biomedical Nanotechnology, 2021, 17(8): 1535-1544. (SCI IF:4.099)
12. Xinping Chen, Weihua Xu, Zhichao Ma, Juan Zhu, Junjie Hu, Xiaojuan Li, and Shengmiao Fu*. Circ_0000215 Exerts Oncogenic Function in Nasopharyngeal Carcinoma by Targeting miR-512-5p . Frontiers in Cell and Developmental Biology, 2021, 9: 1-14. (SCI IF:6.684)
13. Xinping Chen; Weihua Xu; Zhichao Ma; Juan Zhu; Junjie Hu; Xiaojuan Li; Shengmiao Fu*. TTN -AS1 accelerates the growth and migration of nasopharyngeal carcinoma cells via targeting miR-876 -5p/NETO2, Molecular Therapy Oncolytics, 2021, 24: 535-546. (SCI IF:7.2)
14. Xinping Chen, Weihua Xu, Shengmiao Fu*. Association between metoprolol and prognosis of COVID-19 patients. Journal of the American College of Cardiology，2022,1(79): e7. (SCI IF:24.094)
15. Xinping Chen, Weihua Xu, Zhichao Ma, Lan Shen, Yuxu Xie, Xin Zhu, Junjie Hu, Yuliang Zhang, Zhi Fu, and Shengmiao Fu*. Low Expression of BIRC5-206 Promotes Cancer Progression in Nasopharyngeal Carcinoma via Enhancing Expression of Stem Cell Markers. Annals of Clinical & Laboratory Science, 2023, 53(3): 380-388. (SCI IF:1.1)
16. Yonglan Jiang, Wei Gong, Zhenyong Xian, Weihua Xu, Junjie Hu, Zhichao Ma, Huaying Dong, Chong Lin, Shengmiao Fu*, Xinping Chen*. 16S full-length gene sequencing analysis of intestinal flora in breast cancer patients in Hainan Province. Molecular and Cellular Probes, 2023, 71: 101927. (SCI IF:3.3)
17. Xin Zhu, Bin Xiao, Wenwu Zhang, Xiaoyu Song, Wei Gong, Linhai Li, Xingping Chen*. Ring finger protein 157 is a prognostic biomarker and is associated with immune infiltrates in human breast cancer. BIOCELL, 2023, 47(10): 2265-2281. (SCI IF:1.2)
18. Weihua Xu# , Junjie Hu# , Zhichao Ma, Wanyi Feng, Wei Gong, Shengmiao Fu*, Xinping Chen*. Decreased BIRC5-206 promotes epithelial–mesenchymal transition in nasopharyngeal carcinoma through sponging miR-145-5p. Open Medicine, 2024, 19(1): 20241007. (SCI IF:1.7)
19. Wei Gong, Xin Zhu, Wenwu Zhang, Xiaoyu Song, Junjie Hu, Weihua Xu, Zhichao Ma, Bin Xiao,*, Linhai Li*, Xinping Chen*. ZNF775 inhibits MCF-7 breast cancer cell migration by downregulating Wnt5a. Advances in Cancer Biology-Metastasis, 2024, 12: 100129. (ESCI IF:2.0)
20. Min Feng, Wei Gong, Xin Zhu, Juan Zhu, Junjie Hu, Weihua Xu, Zhichao Ma, Shengmiao Fu*, Xinping Chen*. Covalent binding of 5-tetradecyloxy-2-furoic acid (TOFA) and c(RGDfK) and its co-delivery with Lipusu, a novel synergistic strategy to inhibit the proliferation of nasopharyngeal cancer. European journal of pharmaceutical sciences, 2025, 209: 107092. (SCI IF:4.3)
21. Jiayang Jiang, Juanjuan Li, Haoyu Dong, Xinping Chen*, Yanqiong Tang, Xiang Ma, Hong Li, Xue Chi, Xianwen Yang*, Zhu Liu*. Xanthocillin X combats Burkholderia pseudomallei by targeting UDP-N-acetylglucosamine acyltransferase. Microbiological Research, 2025, 298: 128195. (SCI IF:6.9)
22. Wanyi Feng, Sheng Zeng, Donghui Liu, Wei Gong, Junjie Hu, Weihua Xu, Zhichao Ma, Shengmiao Fu*, Xinping Chen*. Single-cell dynamic RNA and glycosylation sequencing reveals the mechanism underlying the differentiation of pluripotent stem cells into hematopoietic stem cells. Human Cell. 2025, 38(4): 110. (SCI IF:3.4)
23. Junjie Hu, Shanshan Xu, Zeng Zeng, Wei Gong, Weihua Xu, Zhichao Ma, Shengmiao Fu, Linhai Li, Bin Xiao, Xinping Chen. Whole genome study and construction of SHERLOCK detection method for endemic strains of Burkholderia pseudomallei in Hainan based on third-generation sequencing. Microbiology Spectrum. 2025.（SCI IF:3.66）
24. Xu W, Ma Z, Gong W, Fu S, Chen X. Functional mechanisms of circular RNA‑encoded peptides and future research strategies and directions in nasopharyngeal carcinoma (Review). Int J Oncol. 2025, 67(4): 82.（SCI IF:4.79）
著作：
1.《临床医学检验技术》副主编，2020 年 8 月，化学工业出版社。
2.《中国肿瘤整合诊治指南（CACA) 血清标志物》编委，2023 年3月，天津科学技术出版社。